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Thelial cells. Suppression of pancreatic cancer cell growth by Triphala in our model was due to induction of apoptosis, which in turn was associated with generation of ROS. Pretreatment of Capan-2 cells with antioxidant NAC blocked ROS generation and completely protected the cells from Triphalainduced apoptosis. Our results also demonstrate that Triphala treatment caused DNA damage resulting in th
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Thelial cells. Suppression of pancreatic cancer cell growth by Triphala in our model was due to induction of apoptosis, which in turn was associated with generation of ROS. Pretreatment of Capan-2 cells with antioxidant NAC blocked ROS generation and completely protected the cells from Triphalainduced apoptosis. Our results also demonstrate that Triphala treatment caused DNA damage resulting in th
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Ed as either HECT domain or RING domain. Ubiquitin is directly conjugated to an internal cysteine residue of HECT domain E3's before being transferred onto the substrate protein [5]. RING E3's do not conjugate ubiquitin, but rather stimulate its transfer from the E2 to the substrate [6,7]. RING domains contain conserved cysteine and histidine residues that chelate zinc ions to provide a structure
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Ana (70112-2699) USA Email: David G Nielsen - dnielsen@tulane.eduPublished: 27 November 2009 Virology Journal 2009, 6:211 doi:10.1186/1743-422X-6-Received: 27 October 2009 Accepted: 27 NovemberThis article is available from: http://www.virologyj.com/content/6/1/211 ?2009 Nielsen; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribu
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Norton.com/myaccount- Create Norton My Account, install setup, change password at www.norton.com/myaccount.
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Nucleation clusters. In calcium phosphate solution, the presence of amelogenin stabilized small particles, aggregates with two or three particles and larger aggregates (pre-nucleation clusters). While needle shaped particles of hydroxyapatite were eventually formed, the amorphous aggregates were stabilized by amelogenin, leading to the statement that amelogenin inhibited (retarded) mineralization
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Ww.molecular-cancer.com/content/11/1/Page 8 ofIllumina Beadchip Human Exon 510 S-Duo (Illumina Inc., San Diego, CA).Additional filesAdditional file 1: Figure S1 TAK733 MTS-based colorimetric cell proliferation assay curves in melanoma cell lines of cutaneous origin according to their BRAF (A) or NRAS (B) mutational status, WT (C) and of uveal origin (D). Modulation of the melanoma cell line viabil
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Pulation. The local government played a key role in reducing the psychological stress. On June 21, the local government took immediate measures to protect its citizens including hourly update of PSI value on television, cancellation of all school activities, offering medical subsidies to treat physical discomfort associated with haze and to provide 1 million free N-95 masks to the needy households